Nuchal translucency (NT) screening is a prenatal test conducted during the first trimester of pregnancy, typically between 11 and 14 weeks of gestation. This non-invasive ultrasound screening measures the thickness of the nuchal fold at the back of the fetus's neck. Increased thickness can be an indicator of chromosomal abnormalities such as Down Syndrome (Trisomy 21), Trisomy 18, and other congenital conditions.