hypothalamic pituitary gonadal axis

What Are Common Disorders of the HPG Axis in Gynecology?

Several disorders can affect the HPG axis:
- PCOS: Characterized by hyperandrogenism, irregular menstrual cycles, and polycystic ovaries.
- Hypothalamic Amenorrhea: Often due to excessive stress, weight loss, or exercise, leading to low GnRH and subsequent low LH and FSH levels.
- Hyperprolactinemia: Elevated prolactin levels can inhibit GnRH secretion, leading to menstrual irregularities and infertility.
- Primary Ovarian Insufficiency: Early depletion of ovarian follicles leading to low estrogen levels and high FSH levels.

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