GnRH is secreted in a pulsatile manner from the hypothalamus. The frequency and amplitude of these pulses regulate the release of LH and FSH from the anterior pituitary. A higher frequency of pulses favors the release of LH, while a lower frequency favors the release of FSH. These gonadotropins then act on the ovaries in females and the testes in males to stimulate the production of sex hormones and gametes.
