Although progestin is beneficial for many, certain individuals should avoid it:
History of Breast Cancer: Progestin can exacerbate hormone-sensitive cancers. Liver Disease: Those with severe liver conditions should avoid progestin due to its metabolism in the liver. Undiagnosed Vaginal Bleeding: Progestin should not be used until the cause of the bleeding is determined. Thromboembolic Disorders: Individuals with a history of blood clots should be cautious.