Premature Ovarian Failure (POF), also known as primary ovarian insufficiency (POI), refers to the loss of normal ovarian function before the age of 40. Unlike menopause, which typically occurs around age 50, POF can occur much earlier and leads to infertility, irregular menstrual cycles, and hormonal imbalances. Women with POF may still have intermittent ovarian function and could occasionally ovulate.
