What Conditions are Associated with Abnormal Estrone Levels?
Various conditions can cause abnormal estrone levels, including:
Polycystic Ovary Syndrome (PCOS): Elevated estrone levels can indicate PCOS, a common endocrine disorder in women of reproductive age. Menopause: Estrone becomes the dominant estrogen during menopause, and its levels can help manage menopausal symptoms. Obesity: Higher levels of estrone are often observed in obese individuals due to increased aromatase activity in adipose tissue. Hormone Replacement Therapy (HRT): Estrone levels are monitored during HRT to ensure appropriate dosing and manage side effects. Estrogen-Secreting Tumors: Elevated estrone levels can be a marker for estrogen-secreting tumors, such as granulosa cell tumors.
