Uterine motility problems can be caused by a variety of factors. Conditions such as uterine fibroids, endometriosis, and adenomyosis can affect the normal contractions of the uterus. Hormonal imbalances, particularly involving estrogen and progesterone, can also play a significant role. Additionally, infections and pelvic inflammatory disease (PID) may lead to scarring and adhesions that impair uterine motility.