Despite the potential benefits, biomarker discovery in gynecology faces several challenges:
Heterogeneity: Gynecological diseases often show considerable heterogeneity, making it difficult to identify universal biomarkers. Sample Quality: The quality and handling of clinical samples can affect the reliability of biomarker studies. Validation: Rigorous validation is required to ensure that potential biomarkers are reliable and clinically useful, which can be time-consuming and costly. Ethical and Regulatory Issues: The use of biomarkers in clinical practice must adhere to ethical guidelines and regulatory requirements.