What are Common Disorders Related to the HPO Axis?
Several disorders can affect the functioning of the HPO axis, including: 1. Polycystic Ovary Syndrome (PCOS): Characterized by an imbalance in reproductive hormones, leading to irregular menstrual cycles and ovulation issues. 2. Hypothalamic Amenorrhea: Caused by insufficient GnRH secretion, often due to stress, excessive exercise, or significant weight loss. 3. Hyperprolactinemia: Elevated levels of prolactin can inhibit GnRH, leading to menstrual irregularities. 4. Premature Ovarian Insufficiency (POI): The loss of normal ovarian function before the age of 40, often leading to infertility.
