The relationship between CVI and gynecology is multifaceted. Hormonal fluctuations, pregnancy, and pelvic congestion syndrome (PCS) are a few factors that can exacerbate venous insufficiency in women. During pregnancy, the growing uterus exerts pressure on the pelvic veins, increasing the risk of CVI. Additionally, hormonal changes during pregnancy and the menstrual cycle can affect vein elasticity and blood flow.