Hormones play a vital role in regulating mood. Fluctuations in estrogen and progesterone levels throughout the menstrual cycle can influence neurotransmitters in the brain, such as serotonin and dopamine. These fluctuations can result in mood swings, irritability, and emotional sensitivity. During pregnancy, the increase in hormones like hCG, estrogen, and progesterone can also affect mood. In menopause, the decline in estrogen levels can lead to mood disturbances, often exacerbating underlying anxiety or depression.