Platelet transfusions are generally administered via an intravenous (IV) line. The process involves: 1. Screening and Matching: Platelets are matched to the recipient's blood type to minimize the risk of reactions. 2. Transfusion: The transfusion is done over a period of 30 minutes to an hour under close medical supervision. 3. Monitoring: Patients are monitored for any adverse reactions, such as fever, chills, or allergic responses.