How are CGG Repeats Related to Fragile X Syndrome?
Fragile X Syndrome (FXS) is a genetic condition that results from the expansion of CGG repeats within the FMR1 gene located on the X chromosome. Normally, this gene contains 5-44 CGG repeats. When the number of repeats increases to a range between 55 and 200, it is called a premutation. If the number exceeds 200, it is considered a full mutation and leads to Fragile X Syndrome, which can cause intellectual disabilities, behavioral challenges, and various physical features.
