The guidelines for gynecological cancer screenings vary based on age, risk factors, and medical history. Generally, women should start getting Pap smears at age 21 and continue every three years until age 29. From age 30 to 65, women should have a Pap smear combined with an HPV test every five years or a Pap smear alone every three years. Women over 65 who have had regular screenings with normal results may discontinue screening.