Manual removal is primarily indicated in the following scenarios: - Retained Placenta: After childbirth, if the placenta does not deliver spontaneously within a reasonable timeframe, manual removal may be necessary. - Incomplete Abortion: If tissue remains in the uterus following a miscarriage or abortion, manual removal is often required. - Postpartum Hemorrhage: In cases of excessive bleeding after childbirth, manually removing retained placental fragments can help control the bleeding.