What Screening and Preventive Measures are Recommended?
For women with Lynch Syndrome, regular screening and preventive measures are crucial. Annual or biennial endometrial biopsy starting at age 30-35 is often recommended to detect endometrial cancer early. Transvaginal ultrasound and CA-125 blood tests may be used for ovarian cancer screening, although their efficacy is less clear. Prophylactic surgery, such as hysterectomy and bilateral salpingo-oophorectomy, may be considered for women who have completed childbearing, as these procedures significantly reduce the risk of gynecologic cancers.