reproductive immunology

What is the Role of the Immune System During Pregnancy?

During pregnancy, the immune system must strike a balance between protecting the body from infections and tolerating the semi-allogeneic fetus. This is achieved through various mechanisms, including the modulation of _T regulatory cells_ and the expression of _HLA-G_ molecules by the placenta. These adaptations prevent the maternal immune system from rejecting the fetus while still providing immune protection.

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