Real World Evidence (RWE) refers to clinical evidence regarding the usage, potential benefits, and risks of a medical product derived from real-world data (RWD). In the realm of Gynecology, RWE is increasingly becoming a pivotal part of clinical decision-making, complementing traditional randomized controlled trials (RCTs). RWE can be derived from various sources, including electronic health records (EHRs), claims databases, patient registries, and even wearable devices.