Complexity of Treatment: Complex treatment regimens can be daunting and lead to non-adherence. Side Effects: Adverse effects from medications can discourage patients from continuing their treatment. Understanding and Education: Lack of knowledge about their condition and the importance of treatment can result in poor adherence. Psychosocial Factors: Mental health issues, such as depression and anxiety, can affect a patient's ability to adhere to treatment plans. Access to Healthcare: Limited access to healthcare providers and medications can hinder adherence.