Polycystic Ovary Syndrome (PCOS): Women with PCOS may have imbalanced FSH and luteinizing hormone (LH) levels, affecting ovulation and fertility. Premature Ovarian Insufficiency (POI): Elevated FSH levels can be a marker of POI, where the ovaries lose function before the age of 40. Menopause: Naturally, FSH levels rise during menopause as the ovaries lose their ability to produce eggs and hormones.