There are multiple causes of undervirilization, including:
Genetic Mutations: Mutations in genes such as the SRY gene, which is critical for male sex determination, can result in undervirilization. Hormonal Imbalances: Inadequate production or action of androgens can lead to this condition. Disorders such as Androgen Insensitivity Syndrome (AIS) are key examples. Enzyme Deficiencies: Deficiencies in enzymes like 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT), can lead to incomplete virilization. Congenital Adrenal Hyperplasia (CAH): This group of genetic disorders affects adrenal gland function, which can impact androgen production.
