Ovarian dysgenesis can be caused by genetic mutations or chromosomal abnormalities. One of the most well-known causes is Turner syndrome, where individuals typically have a 45,X karyotype, meaning they have a missing or structurally altered X chromosome. Other genetic conditions like Swyer syndrome (46,XY gonadal dysgenesis) can also result in ovarian dysgenesis. Mutations in genes such as FSHR (follicle-stimulating hormone receptor) and BMP15 may contribute to the condition, impacting ovarian development and function.
