The reduction in estrogen caused by GnRH agonists can lead to several side effects:
1. Menopausal Symptoms: Hot flashes, night sweats, and vaginal dryness are common due to the hypoestrogenic state. 2. Bone Density Loss: Prolonged use can result in decreased bone mineral density, increasing the risk of osteoporosis. 3. Mood Changes: Some women may experience mood swings, depression, or anxiety. 4. Headaches: These can occur, particularly during the initial phase of treatment.
