Hormonal contraceptives should be prescribed based on the patient's health status and preferences. Combined oral contraceptives (COCs) are generally safe for most women, but contraindications such as a history of thromboembolic disorders, certain cancers, and uncontrolled hypertension must be considered. For women who cannot take COCs, progestin-only pills or long-acting reversible contraceptives like IUDs may be appropriate alternatives.