Valacyclovir is typically administered orally in the form of tablets. The dosage and duration of treatment depend on the specific condition being treated. For initial episodes of genital herpes, the usual dosage is 1 gram twice daily for 10 days. For recurrent episodes, the dosage is 500 mg twice daily for 3 days. For suppression therapy, the dosage can range from 500 mg to 1 gram once daily.