Immediate treatment is critical to reduce the toxic effects of ethylene glycol. The mainstays of treatment include:
Administration of antidotes such as fomepizole or ethanol to inhibit the enzyme alcohol dehydrogenase, thereby preventing the formation of toxic metabolites. Hemodialysis to remove ethylene glycol and its toxic metabolites from the blood. Supportive care, including intravenous fluids, correction of metabolic acidosis with sodium bicarbonate, and monitoring of vital signs and renal function.