Progestins act on progesterone receptors in the body to produce effects similar to those of natural progesterone. They help prepare the endometrium (lining of the uterus) for implantation of a fertilized egg and prevent the overgrowth of the endometrium, which can lead to conditions like endometrial hyperplasia. In contraceptives, progestins prevent ovulation and thicken cervical mucus to block sperm entry.
