How do BRCA1 and BRCA2 Mutations Affect Gynecological Health?
Women with BRCA1 or BRCA2 mutations have a higher risk of developing gynecological cancers. Specifically, BRCA1 mutations are associated with up to a 65% risk of breast cancer and a 39% risk of ovarian cancer by age 70. BRCA2 mutations also increase these risks but to a slightly lesser extent, with a 45% risk of breast cancer and up to a 17% risk of ovarian cancer.
