Endometrial (uterine) cancer - Gynecology

What is Endometrial Cancer?

Endometrial cancer, also known as uterine cancer, is a type of cancer that originates in the lining of the uterus called the endometrium. It is the most common type of uterine cancer and primarily affects women post-menopause.

What are the Risk Factors?

Several risk factors are associated with endometrial cancer:
Age: Most cases occur in women over the age of 50.
Obesity: Excess body fat can alter hormone levels, increasing risk.
Hormone Therapy: Use of estrogen without progesterone increases the risk.
Family History: A family history of endometrial or colorectal cancer.
PCOS: Women with polycystic ovary syndrome may be at higher risk.

What are the Symptoms?

Early detection of endometrial cancer is crucial. Common symptoms include:
Abnormal vaginal bleeding or discharge
Pelvic pain
Pain during intercourse
Unexplained weight loss

How is it Diagnosed?

Diagnosis typically involves several steps:
Pelvic Examination: A physical exam to check for abnormalities.
Transvaginal Ultrasound: Imaging to assess the thickness of the endometrium.
Endometrial Biopsy: A sample of the endometrial tissue is taken for analysis.
Hysteroscopy: A procedure to examine the inside of the uterus.

What are the Treatment Options?

Treatment varies depending on the stage and grade of the cancer but often includes:
Surgery: The primary treatment, usually involving a hysterectomy.
Radiation Therapy: Used to kill remaining cancer cells post-surgery.
Chemotherapy: Employed in advanced stages of the disease.
Hormone Therapy: Utilized when cancer cells have hormone receptors.

What is the Prognosis?

The prognosis for endometrial cancer is generally good if detected early. The 5-year survival rate is high for early-stage cancer but decreases as the cancer advances. Regular follow-ups and monitoring are essential for managing the disease.

How can it be Prevented?

Preventive measures include:
Maintaining a healthy weight
Using oral contraceptives: These can reduce the risk if used for several years.
Managing conditions like diabetes and PCOS
Regular pelvic exams and screenings

Conclusion

Endometrial cancer is a significant concern in gynecology, but with early detection and appropriate treatment, the prognosis is often favorable. Awareness of risk factors, symptoms, and preventive measures can aid in early diagnosis and treatment, enhancing the quality of life for those affected.



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