Downstage the Tumor: It can shrink the tumor, making it more amenable to surgical removal. Assess Tumor Response: It helps in evaluating the tumor's response to chemotherapy, which might predict the overall prognosis. Reduce Surgical Morbidity: Smaller tumors often result in less extensive surgery, potentially lowering the risk of complications. Immediate Systemic Treatment: It provides early treatment of micrometastatic disease.
