Recurrent Pregnancy Loss: Women who experience multiple miscarriages may undergo karyotype analysis to check for genetic abnormalities. Infertility: Both partners may be tested to identify potential chromosomal issues that could be affecting their ability to conceive. Prenatal Testing: Pregnant women may have karyotype analysis through procedures like amniocentesis or chorionic villus sampling (CVS) to detect chromosomal disorders in the fetus. Developmental Delays and Congenital Anomalies: Children born with developmental delays or congenital anomalies may undergo karyotype analysis to identify underlying genetic causes.