Denosumab is typically prescribed for the following conditions in gynecology: - Osteoporosis in postmenopausal women: To increase bone mass and reduce the risk of fractures. - Women receiving adjuvant aromatase inhibitor therapy for breast cancer: These women are at increased risk of developing osteoporosis due to the estrogen-lowering effects of aromatase inhibitors. - Prevention of skeletal-related events: In women with bone metastases from solid tumors.