Zoledronic acid is a bisphosphonate medication commonly used in the treatment of various bone diseases. It works by inhibiting osteoclast-mediated bone resorption, thereby increasing bone density and reducing the risk of fractures. In the context of gynecology, zoledronic acid is primarily used for the management of osteoporosis, particularly postmenopausal osteoporosis, and to prevent skeletal-related events in patients with certain cancers.