What is the Role of Epigenetics in Gynecologic Cancers?
Epigenetic alterations are pivotal in the development and progression of various gynecologic cancers such as ovarian, endometrial, and cervical cancers. For example, abnormal DNA methylation of tumor suppressor genes can lead to their silencing and uncontrolled cell proliferation. Understanding these changes can aid in early diagnosis and the development of targeted therapies.