What is the Risk of Cancer Associated with BRCA1 and BRCA2 Mutations?
Women with BRCA1 mutations have a 55-65% risk of developing breast cancer by age 70, while those with BRCA2 mutations have around a 45% risk. For ovarian cancer, BRCA1 mutation carriers have a 39% risk, and BRCA2 mutation carriers have an 11-17% risk. Men with BRCA mutations also have an elevated risk of breast cancer and other cancers, including prostate cancer.