Stage IV vulvar cancer is the most advanced form of vulvar cancer, indicating that the cancer has spread beyond the vulva to other parts of the body. This stage is subdivided into IVA and IVB. In stage IVA, the cancer has invaded structures such as the bladder or rectum, or has spread to distant lymph nodes. In stage IVB, the cancer has metastasized to distant organs such as the lungs or bones.