Despite its advantages, PGD has some limitations and risks:
PGD is an invasive procedure that involves embryo biopsy, which may carry a risk of embryo damage. The accuracy of PGD is high, but not 100%, so there is a small chance of misdiagnosis. PGD cannot detect all genetic conditions; it is limited to the specific conditions being tested. The procedure is expensive and may not be covered by all insurance plans. Ethical considerations may arise regarding the selection and disposal of embryos based on genetic testing.