The most common causes of acquired platelet function disorders include the use of certain medications, systemic diseases, and other conditions. Key causes include:
Medications: Nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin, and certain antibiotics can impair platelet function. Systemic Diseases: Conditions such as chronic kidney disease, liver disease, and myeloproliferative disorders can affect platelet function. Nutritional Deficiencies: Deficiencies in vitamin B12, folate, and iron can lead to platelet dysfunction. Autoimmune Disorders: Diseases like systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) can impact platelet function.
