During pregnancy, the body metabolizes caffeine more slowly, which means it stays in the bloodstream longer. High levels of caffeine intake during pregnancy have been associated with an increased risk of miscarriage, preterm birth, and low birth weight. The American College of Obstetricians and Gynecologists (ACOG) recommends that pregnant women limit their caffeine intake to less than 200 milligrams per day, roughly equivalent to one 12-ounce cup of coffee.