The process of karyotyping involves several steps:
Sample Collection: Cells are usually collected from blood, amniotic fluid, or chorionic villi. Cell Culture: The collected cells are cultured in a laboratory to encourage them to divide. Chromosome Preparation: The cells are then treated to halt division at the metaphase stage, where chromosomes are most visible. Staining: The chromosomes are stained to make them more visible under a microscope. Analysis: A specialist examines the stained chromosomes, photographs them, and arranges them into a karyotype for analysis.