karyotyping

How is Karyotyping Performed?

The process of karyotyping involves several steps:
Sample Collection: Cells are usually collected from blood, amniotic fluid, or chorionic villi.
Cell Culture: The collected cells are cultured in a laboratory to encourage them to divide.
Chromosome Preparation: The cells are then treated to halt division at the metaphase stage, where chromosomes are most visible.
Staining: The chromosomes are stained to make them more visible under a microscope.
Analysis: A specialist examines the stained chromosomes, photographs them, and arranges them into a karyotype for analysis.

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