Diagnosis typically involves a physical examination and laboratory tests: - Urine Analysis and Culture: For UTIs, a urine sample is taken to identify the presence of E. coli and determine its antibiotic sensitivity. - Vaginal Swabs: For bacterial vaginosis or other vaginal infections, a swab of vaginal discharge can be examined microscopically and cultured to identify E. coli. - Blood Tests: In cases of severe infection or suspected pelvic inflammatory disease, blood tests may be conducted to assess the extent of the infection.