How does genetic predisposition influence ovarian cancer risk?
Genetic predisposition plays a major role in the development of ovarian cancer. Mutations in certain genes, such as BRCA1 and BRCA2, significantly increase the risk. Women with these mutations have a 10-30% risk of developing ovarian cancer by age 70. Additionally, conditions like Lynch syndrome (hereditary nonpolyposis colorectal cancer) are also associated with an increased risk of ovarian cancer.
