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How Does Free T3 Affect Menstrual Cycles?
Thyroid hormones have a direct influence on the
hypothalamic-pituitary-ovarian axis
. Abnormal levels of free T3 can disrupt the release of
gonadotropin-releasing hormone (GnRH)
, which in turn affects the secretion of
luteinizing hormone (LH)
and
follicle-stimulating hormone (FSH)
. This disruption can lead to irregular menstrual cycles or even amenorrhea (absence of menstruation).
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