Clomiphene functions by blocking estrogen receptors in the hypothalamus, which is a key brain region involved in the hormonal regulation of ovulation. This blockage tricks the body into thinking there is a low level of estrogen, leading to an increased release of gonadotropin-releasing hormone (GnRH). GnRH stimulates the pituitary gland to release more follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are crucial for follicle development and ovulation.
