mahesh n sangrithi - Gynecology

Author Information

Dr. Mahesh N. Sangrithi is affiliated with KK Women's and Children's Hospital, Division of Obstetrics and Gynecology, and Duke-NUS Graduate Medical School, Cancer Stem Cell Biology/OBGYN ACP, both located in Singapore. His research focuses on various aspects of reproductive biology, including embryogenesis, spermatogenesis, and X chromosome dosage compensation. His work is crucial in understanding underlying mechanisms that affect fertility and reproductive health.

Research Contributions

Dr. Sangrithi has made significant contributions to the field of reproductive biology and genomics. Some of his notable works include the direct reprogramming of human embryonic cells to trophoblast stem cells, isolation of spermatogenic cells from the cynomolgus macaque testis using flow cytometry, and creating a single-cell transcriptome atlas of marsupial embryogenesis and X inactivation. His research has implications for understanding fertility, genetic integrity, and developmental biology.

Aliases

Mahesh N Sangrithi, Mahesh Sangrithi

Publication and Citation Metrics

Publication Year	Title	DOI
2021	Direct reprogramming of human embryonic to trophoblast stem cells	10.1101/2021.08.18.456785
2021	Isolation of spermatogenic cells from the cynomolgus macaque testis with flow cytometry	10.1016/j.xpro.2021.100294
2021	Publisher Correction: A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation	10.1038/s41586-020-03110-w
2020	A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation	10.1038/s41586-020-2629-6
2020	The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes	10.1038/s41467-020-16441-z
2020	Single-Cell RNA Sequencing of the Cynomolgus Macaque Testis Reveals Conserved Transcriptional Profiles during Mammalian Spermatogenesis	10.1016/j.devcel.2020.07.018
2020	Publisher Correction: A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation	10.1038/s41586-020-2840-5
2018	Mammalian X Chromosome Dosage Compensation: Perspectives From the Germ Line	10.1002/bies.201800024
2018	SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice	10.1016/j.devcel.2018.10.004
2017	Non-Canonical and Sexually Dimorphic X Dosage Compensation States in the Mouse and Human Germline	10.1016/j.devcel.2016.12.023