Chlamydia trachomatis - Gynecology

What is Chlamydia trachomatis?

Chlamydia trachomatis is a bacterium that causes the most common sexually transmitted infection (STI) worldwide. It primarily affects the genital tract but can also infect the rectum and throat. In women, it can lead to severe reproductive health issues if left untreated.

How is it transmitted?

Chlamydia trachomatis is transmitted through sexual contact with an infected person. This includes vaginal, anal, and oral sex. It can also be passed from an infected mother to her baby during childbirth, causing neonatal infections.

What are the symptoms?

Many people infected with Chlamydia trachomatis are asymptomatic, meaning they show no symptoms. When symptoms do occur, they can include:
Abnormal vaginal discharge
Burning sensation during urination
Lower abdominal pain
Painful intercourse
Bleeding between periods
In men, symptoms may involve discharge from the penis, burning during urination, and pain or swelling in one or both testicles.

What are the complications?

If left untreated, Chlamydia trachomatis can lead to serious complications such as pelvic inflammatory disease (PID), which can cause chronic pelvic pain, infertility, and ectopic pregnancy. It can also increase the risk of acquiring or transmitting HIV.

How is it diagnosed?

Diagnosis typically involves nucleic acid amplification tests (NAATs), which are highly sensitive and specific. These tests can be performed on urine samples or swabs from the cervix, urethra, rectum, or throat.

What is the treatment?

The standard treatment for Chlamydia trachomatis involves antibiotics, most commonly azithromycin (single dose) or doxycycline (taken twice daily for seven days). It is important to complete the entire course of antibiotics and to abstain from sexual activity until the infection is fully cleared.

How can it be prevented?

Prevention strategies include the use of condoms during sexual activity, regular STI screenings, and maintaining a monogamous relationship with an uninfected partner. Educating individuals about safe sex practices is also crucial in preventing the spread of Chlamydia trachomatis.

What are the guidelines for screening?

The Centers for Disease Control and Prevention (CDC) recommends annual screening for sexually active women under 25 and older women with risk factors such as new or multiple sex partners. Pregnant women should also be screened during their first prenatal visit.

What is the impact on pregnancy?

Chlamydia trachomatis during pregnancy can lead to adverse outcomes such as preterm labor, low birth weight, and neonatal infections like pneumonia and conjunctivitis. Therefore, timely diagnosis and treatment are crucial for the health of both the mother and the baby.



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