causes of miscarriage - Gynecology

What is a Miscarriage?

A miscarriage is the spontaneous loss of a pregnancy before the 20th week. It is a common occurrence, with about 10-20% of known pregnancies ending in miscarriage. However, the actual number is likely higher because many miscarriages occur before a woman even knows she is pregnant.

What are the common causes of miscarriage?

There are several potential causes of miscarriage, which can generally be categorized into genetic, anatomical, hormonal, and lifestyle factors.

Genetic Factors

The most common cause of miscarriage is chromosomal abnormalities in the developing fetus. These abnormalities occur when the embryo has an incorrect number of chromosomes, which can lead to developmental issues. Examples include trisomy (an extra chromosome) and monosomy (a missing chromosome).

Anatomical Factors

Issues with the mother's reproductive organs can also lead to miscarriage. These include:
Uterine abnormalities such as a septate uterus, fibroids, or adhesions from previous surgeries.
Incompetent cervix, where the cervix weakens and opens too early during pregnancy.

Hormonal Factors

Hormonal imbalances can interfere with a healthy pregnancy. Conditions such as Polycystic ovary syndrome (PCOS) and thyroid disorders can increase the risk of miscarriage. Additionally, insufficient production of the hormone progesterone may prevent the embryo from implanting properly in the uterus.

Infections

Certain infections can lead to miscarriage, particularly if they go untreated. These include:

Immune System Disorders

Some autoimmune conditions, like antiphospholipid syndrome or lupus, can cause the immune system to mistakenly attack the embryo, leading to miscarriage.

Lifestyle Factors

Several lifestyle factors can increase the risk of miscarriage:

How can one reduce the risk of miscarriage?

While not all miscarriages are preventable, certain steps can help reduce the risk:
Maintain a healthy lifestyle, including a balanced diet and regular exercise.
Avoid smoking, alcohol, and illicit drugs.
Manage chronic health conditions such as diabetes and thyroid disorders.
Attend regular prenatal check-ups and follow medical advice.
Ensure vaccinations are up to date to prevent infections that could harm the pregnancy.

When should one seek medical advice?

If you experience symptoms like vaginal bleeding, cramping, or back pain during pregnancy, it is crucial to seek medical advice immediately. Early intervention can sometimes help manage the underlying issues and improve outcomes.

Conclusion

Miscarriage is a complex issue with multiple potential causes. Understanding these causes can help individuals and healthcare providers take proactive steps to reduce risks and manage complications effectively.



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