Lower Urinary Tract infections - Gynecology

What is a Lower Urinary Tract Infection?

A lower urinary tract infection (UTI) primarily affects the bladder and urethra. Commonly known as cystitis, it is a prevalent condition in women due to anatomical factors and can lead to discomfort and potential complications if not properly managed.

Causes and Risk Factors

Lower UTIs are primarily caused by bacterial invasion, most commonly by Escherichia coli (E. coli) from the gastrointestinal tract. Risk factors include sexual activity, certain types of contraception like diaphragms or spermicides, menopause, and a history of UTIs. Women have a shorter urethra, which facilitates the easier ascent of bacteria into the bladder.

Symptoms

Typical symptoms include a frequent and urgent need to urinate, a burning sensation during urination, cloudy or strong-smelling urine, and lower abdominal pain. Some women may also experience hematuria (blood in urine) and pelvic discomfort.

Diagnosis

Diagnosis of a lower UTI often involves a urinalysis, where a urine sample is examined for the presence of white blood cells, red blood cells, and bacteria. A urine culture may also be conducted to identify the specific bacterial strain and its antibiotic sensitivities.

Treatment

The standard treatment for lower UTIs involves a course of antibiotics. Commonly prescribed antibiotics include nitrofurantoin, trimethoprim-sulfamethoxazole, and fosfomycin. It's important for patients to complete the full course of antibiotics even if symptoms improve to prevent recurrence and resistance.

Prevention

Preventive measures include proper hydration, urinating after sexual intercourse, wiping from front to back, avoiding irritating feminine products, and choosing alternative forms of contraception if necessary. For women who experience frequent UTIs, prophylactic antibiotics may be recommended.

Complications

If left untreated, a lower UTI can ascend to the kidneys, causing a more severe infection known as pyelonephritis. This can lead to more serious health issues, including kidney damage and sepsis.

Recurrent UTIs

Recurrent UTIs are defined as having two or more infections in six months or three or more in one year. This can be linked to genetic factors, behavioral factors, or anatomical differences. Management may include lifestyle modifications, continuous low-dose antibiotics, or post-coital prophylaxis.

UTIs During Pregnancy

Pregnant women are at an increased risk of UTIs due to physiological changes such as urinary stasis and a dilated urinary tract. Untreated UTIs in pregnancy can lead to complications such as preterm labor and low birth weight. Screening and appropriate antibiotic treatment are crucial during pregnancy.

Special Considerations

In postmenopausal women, the loss of estrogen can lead to changes in the urinary tract, increasing susceptibility to UTIs. Topical estrogen therapy can sometimes be beneficial in reducing the frequency of infections. Additionally, women with diabetes are at higher risk due to immunosuppression and poor glycemic control.

Conclusion

Lower urinary tract infections are a common but manageable condition in gynecology. Understanding the causes, recognizing symptoms early, and adhering to preventive measures can significantly reduce the incidence and impact of UTIs. Proper diagnosis and treatment are essential to prevent complications and ensure overall urinary health.



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